Health care of Kyrgyzstan
Zdravoohraneniye Kyrgyzstana

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Anxiety and depression among tuberculosis patients in Kyrgyzstan: prevalence and associations with age and treatment duration

https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
Anxiety and depression among tuberculosis patients in Kyrgyzstan: prevalence and associations with age and treatment duration
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Abstract About the authors References

Abstract

Introduction. Tuberculosis remains a major public health problem in Kyrgyzstan, and anxiety and depression are common comorbid conditions that affect treatment adherence and outcomes. However, data on the psychoemotional status of patients with tuberculosis in the country remain limited. Objective. To assess the levels of anxiety and depression among outpatients with pulmonary tuberculosis and to determine their association with age and duration of therapy using the Hospital Anxiety and Depression Scale (HADS). Materials and Methods. A cross-sectional analytical study was conducted among 401 patients receiving outpatient treatment in four regions of Kyrgyzstan. Anxiety (HADS-A) and depression (HADS-D) levels were assessed using the HADS instrument. Data were analyzed by age groups (18–29, 3049, ≥50 years) and treatment duration (<4, 4–12, >12 months). Nonparametric statistical methods (Kruskal–Wallis test and Pearson’s χ² test) were applied. Clinically significant symptomatology was defined at a cut-off value of ≥8 points. Data collection was performed using the KoBoToolbox platform, and statistical analysis and graphical visualization were conducted in R version 4.4.3 (2025-02-28, ucrt) using RStudio version 2025.09.2 (Build 418) (Posit Software, USA). Results and Discussion. Elevated anxiety (≥8 points on HADS-A) was identified in 29.4% of patients, while elevated depression (≥8 points on HADSD) was detected in 39.4%. Anxiety levels were significantly higher in the 30–49-year age group (p=0.035), whereas depression was more prevalent among patients aged ≥50 years (p=0.0098). Treatment duration was not associated with anxiety levels; however, a borderline trend toward increased depression was observed among patients receiving therapy for more than 12 months. Conclusions. Anxiety and depression are highly prevalent among patients with tuberculosis. Depression is more common in patients aged over 50 years, whereas anxiety predominates in middle-aged patients. These findings underscore the need for routine mental health screening and strengthened psychosocial support within outpatient tuberculosis care programs in Kyrgyzstan.

About the authors

Байызбекова Эльмира Алчинбековна, специалист по укреплению здоровья Центра медицины окружающей среды, экологии человека и питания, Национального института общественного здоровья Министерства здравоохранения, Бишкек, Кыргызская Республика

Baiyzbekova Elmira Alchinbekovna, Health Promotion Specialist, Center for Environmental Medicine, Human Ecology, and Nutrition, National Institute of Public Health, Ministry of Health, Bishkek, Kyrgyz Republic

Байызбекова Элмира Алчынбековна, Саламаттыкты сактоо министрлигинин Коомдук саламаттыкты сактоо боюнча улуттук институтунун Айлана-чөйрөнү коргоо медицинасы, адам экологиясы жана тамактануу борборунун Ден соолуктун чыңдоо боюнча адиси, Бишкек, Кыргыз Республикасы

References

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2. Ambaw F., Mayston R., Hanlon C., Alem A. Incidence of depression in people with newly diagnosed tuberculosis in Ethiopia: a cohort study. Global Mental Health. 2020;7:e1. DOI: https://doi.org/10.1017/gmh.2019.27 URL: https://www.cambridge.org/core/journals/global-mental-health/article/incidence-of-depression-in-people-with-newly-diag nosed-tuberculosis-in-ethiopia-a-cohort-study/D31BBF368691480D0FCEAD5FAC7A86DF?utm_source=chatgpt.com

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5. Lee G., Scuffell J., Galea J.T., Shin S.S., Magill E., Jaramillo E., Sweetland A.C. Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis. International Journal of Tuberculosis and Lung Disease. 2020;24(12):1279– 1284. DOI: 10.5588/ijtld.20.0458. URL: https://pubmed.ncbi.nlm.nih.gov/33317672/

6. Liu X., Bai X., Ren R., Tan L., Zhang Y., Lan H., Yang Q., He J., Tang X. Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study. Frontiers in Psychiatry. 2022;13:985823. DOI: 10.3389/fpsyt.2022.985823. URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.985823/full

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8. Patel, N., Patel, H., Varu, J., Gandhi, R., Murugan, Y. The Invisible Toll: Unveiling the Prevalence and Predictors of Depression and Anxiety Among Pulmonary Tuberculosis (TB) Patients and Their Households in Gujarat, India. Cureus. 2024;16(7):e65015. DOI: 10.7759/cureus.65015. URL: https://www.cureus.com/articles/275659-the-invisible-toll-unveiling-the-prevalence-and-pre dictors-of-depression-and-anxiety-among-pulmonary-tuberculosis-tb-patients-and-their-households-in-gujarat-india

9. Samal J., Dehury R.K., Thomas M.B., Singh H. Prevalence and predictors of depression in tuberculosis patients in India: a syste- matic review and meta-analysis. Discover Mental Health. 2025;5(1):104. DOI: 10.1007/s44192-025-00248-9. URL: https://pub- med.ncbi.nlm.nih.gov/40650839/

10. Shen R., Zong K., Liu J., Zhang L. Risk Factors for Depression in Tuberculosis Patients: A Meta-Analysis. Neuropsychiatric Disease and Treatment. 2022;18:847–866. DOI: 10.2147/NDT.S347579. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC 9012238/

11. World Health organization. Global tuberculosis report 2022. Geneva; 2022. URL: https://iris.who.int/bitstream/handle/10665/363 752/ 9789240061729-eng.pdf

12. World Health Organization. World mental health report: transforming mental health for all. Geneva; 2022. URL:https://iris.who.int/ bitstream /handle/10665/356119/9789240049338-eng.pdf

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14. World Health Organization. Operational Handbook on Tuberculosis. Module 6: Tuberculosis and Comorbidities. Mental health conditions and substance use disorders. Section 3: Identifying and managing care for mental health conditions and substance use disorders in people affected by TB. WHO TB Knowledge Sharing Platform. URL: https://tbksp.who.int/en/node/2649

1. Agbeko C.K., Mallah M.A., He B., Liu Q., Song H., Wang J. Mental Health Status and Its Impact on TB Treatment and Its Out comes: A Scoping Literature Review. Frontiers in Public Health. 2022;10:855515. DOI: 10.3389/fpubh.2022.855515. URL: https://www.frontiersin.org/articles/10.3389/fpubh.2022.855515/full

2. Ambaw F., Mayston R., Hanlon C., Alem A. Incidence of depression in people with newly diagnosed tuberculosis in Ethiopia: a cohort study. Global Mental Health. 2020;7:e1. DOI: https://doi.org/10.1017/gmh.2019.27 URL: https://www.cambridge.org/core/journals/global-mental-health/article/incidence-of-depression-in-people-with-newly-diag nosed-tuberculosis-in-ethiopia-a-cohort-study/D31BBF368691480D0FCEAD5FAC7A86DF?utm_source=chatgpt.com

3. Duko B., Bedaso A., Ayano G. The prevalence of depression among patients with tuberculosis: a systematic review and meta- analysis. Annals of General Psychiatry. 2020;19:30. DOI: 10.1186/s12991-020-00281-8. URL: https://annals-general-psychiatry. biomedcentral.com/articles/10.1186/s12991-020-00281-8

4. Fukunaga R, Pierre P, Williams JK, Briceno-Robaugh R, Kalibala S, Peterson M, et al. Prioritizing Mental Health within HIV and Tuberculosis Services in PEPFAR. Emerg Infect Dis. 2024;30(4):1-5. DOI: 10.3201/eid3004.231726 URL: https://wwwnc.cdc. gov/eid/article/30/4/23-1726_article

5. Lee G., Scuffell J., Galea J.T., Shin S.S., Magill E., Jaramillo E., Sweetland A.C. Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis. International Journal of Tuberculosis and Lung Disease. 2020;24(12):1279– 1284. DOI: 10.5588/ijtld.20.0458. URL: https://pubmed.ncbi.nlm.nih.gov/33317672/

6. Liu X., Bai X., Ren R., Tan L., Zhang Y., Lan H., Yang Q., He J., Tang X. Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study. Frontiers in Psychiatry. 2022;13:985823. DOI: 10.3389/fpsyt.2022.985823. URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.985823/full

7. Panibatla, V., Nagaraja, S. B., Mohan, D., Kizhakkethil, S. M. P., Sangeetha, M. D. Depression and Anxiety among Tuberculosis Patients: A Systematic Review and Meta-analysis. Indian Journal of Social Psychiatry 40(4):p 326-340, Oct–Dec 2024. DOI:10.4103/ijsp.ijsp_222_23. URL:https://journals.lww.com/ijsp/fulltext/2024/40040/ depression_and_anxiety_ among_tuber culosis. 2.aspx

8. Patel, N., Patel, H., Varu, J., Gandhi, R., Murugan, Y. The Invisible Toll: Unveiling the Prevalence and Predictors of Depression and Anxiety Among Pulmonary Tuberculosis (TB) Patients and Their Households in Gujarat, India. Cureus. 2024;16(7):e65015. DOI: 10.7759/cureus.65015. URL: https://www.cureus.com/articles/275659-the-invisible-toll-unveiling-the-prevalence-and-pre dictors-of-depression-and-anxiety-among-pulmonary-tuberculosis-tb-patients-and-their-households-in-gujarat-india

9. Samal J., Dehury R.K., Thomas M.B., Singh H. Prevalence and predictors of depression in tuberculosis patients in India: a syste- matic review and meta-analysis. Discover Mental Health. 2025;5(1):104. DOI: 10.1007/s44192-025-00248-9. URL: https://pub- med.ncbi.nlm.nih.gov/40650839/

10. Shen R., Zong K., Liu J., Zhang L. Risk Factors for Depression in Tuberculosis Patients: A Meta-Analysis. Neuropsychiatric Disease and Treatment. 2022;18:847–866. DOI: 10.2147/NDT.S347579. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC 9012238/

11. World Health organization. Global tuberculosis report 2022. Geneva; 2022. URL: https://iris.who.int/bitstream/handle/10665/363 752/ 9789240061729-eng.pdf

12. World Health Organization. World mental health report: transforming mental health for all. Geneva; 2022. URL:https://iris.who.int/ bitstream /handle/10665/356119/9789240049338-eng.pdf

13. World Health Organization. WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities - mental health conditions. Geneva; 2023. URL: https://iris.who.int/bitstream/handle/10665/373829/9789240082557-eng.pdf

14. World Health Organization. Operational Handbook on Tuberculosis. Module 6: Tuberculosis and Comorbidities. Mental health conditions and substance use disorders. Section 3: Identifying and managing care for mental health conditions and substance use disorders in people affected by TB. WHO TB Knowledge Sharing Platform. URL: https://tbksp.who.int/en/node/2649

1. Agbeko C.K., Mallah M.A., He B., Liu Q., Song H., Wang J. Mental Health Status and Its Impact on TB Treatment and Its Out comes: A Scoping Literature Review. Frontiers in Public Health. 2022;10:855515. DOI: 10.3389/fpubh.2022.855515. URL: https://www.frontiersin.org/articles/10.3389/fpubh.2022.855515/full

2. Ambaw F., Mayston R., Hanlon C., Alem A. Incidence of depression in people with newly diagnosed tuberculosis in Ethiopia: a cohort study. Global Mental Health. 2020;7:e1. DOI: https://doi.org/10.1017/gmh.2019.27 URL: https://www.cambridge.org/core/journals/global-mental-health/article/incidence-of-depression-in-people-with-newly-diag nosed-tuberculosis-in-ethiopia-a-cohort-study/D31BBF368691480D0FCEAD5FAC7A86DF?utm_source=chatgpt.com

3. Duko B., Bedaso A., Ayano G. The prevalence of depression among patients with tuberculosis: a systematic review and meta- analysis. Annals of General Psychiatry. 2020;19:30. DOI: 10.1186/s12991-020-00281-8. URL: https://annals-general-psychiatry. biomedcentral.com/articles/10.1186/s12991-020-00281-8

4. Fukunaga R, Pierre P, Williams JK, Briceno-Robaugh R, Kalibala S, Peterson M, et al. Prioritizing Mental Health within HIV and Tuberculosis Services in PEPFAR. Emerg Infect Dis. 2024;30(4):1-5. DOI: 10.3201/eid3004.231726 URL: https://wwwnc.cdc. gov/eid/article/30/4/23-1726_article

5. Lee G., Scuffell J., Galea J.T., Shin S.S., Magill E., Jaramillo E., Sweetland A.C. Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis. International Journal of Tuberculosis and Lung Disease. 2020;24(12):1279– 1284. DOI: 10.5588/ijtld.20.0458. URL: https://pubmed.ncbi.nlm.nih.gov/33317672/

6. Liu X., Bai X., Ren R., Tan L., Zhang Y., Lan H., Yang Q., He J., Tang X. Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study. Frontiers in Psychiatry. 2022;13:985823. DOI: 10.3389/fpsyt.2022.985823. URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.985823/full

7. Panibatla, V., Nagaraja, S. B., Mohan, D., Kizhakkethil, S. M. P., Sangeetha, M. D. Depression and Anxiety among Tuberculosis Patients: A Systematic Review and Meta-analysis. Indian Journal of Social Psychiatry 40(4):p 326-340, Oct–Dec 2024. DOI:10.4103/ijsp.ijsp_222_23. URL:https://journals.lww.com/ijsp/fulltext/2024/40040/ depression_and_anxiety_ among_tuber culosis. 2.aspx

8. Patel, N., Patel, H., Varu, J., Gandhi, R., Murugan, Y. The Invisible Toll: Unveiling the Prevalence and Predictors of Depression and Anxiety Among Pulmonary Tuberculosis (TB) Patients and Their Households in Gujarat, India. Cureus. 2024;16(7):e65015. DOI: 10.7759/cureus.65015. URL: https://www.cureus.com/articles/275659-the-invisible-toll-unveiling-the-prevalence-and-pre dictors-of-depression-and-anxiety-among-pulmonary-tuberculosis-tb-patients-and-their-households-in-gujarat-india

9. Samal J., Dehury R.K., Thomas M.B., Singh H. Prevalence and predictors of depression in tuberculosis patients in India: a syste- matic review and meta-analysis. Discover Mental Health. 2025;5(1):104. DOI: 10.1007/s44192-025-00248-9. URL: https://pub- med.ncbi.nlm.nih.gov/40650839/

10. Shen R., Zong K., Liu J., Zhang L. Risk Factors for Depression in Tuberculosis Patients: A Meta-Analysis. Neuropsychiatric Disease and Treatment. 2022;18:847–866. DOI: 10.2147/NDT.S347579. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC 9012238/

11. World Health organization. Global tuberculosis report 2022. Geneva; 2022. URL: https://iris.who.int/bitstream/handle/10665/363 752/ 9789240061729-eng.pdf

12. World Health Organization. World mental health report: transforming mental health for all. Geneva; 2022. URL:https://iris.who.int/ bitstream /handle/10665/356119/9789240049338-eng.pdf

13. World Health Organization. WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities - mental health conditions. Geneva; 2023. URL: https://iris.who.int/bitstream/handle/10665/373829/9789240082557-eng.pdf

14. World Health Organization. Operational Handbook on Tuberculosis. Module 6: Tuberculosis and Comorbidities. Mental health conditions and substance use disorders. Section 3: Identifying and managing care for mental health conditions and substance use disorders in people affected by TB. WHO TB Knowledge Sharing Platform. URL: https://tbksp.who.int/en/node/2649

Keywords
Age , Kyrgyzstan , Tuberculosis , Anxiety , Depression , HADS , Mental health , Treatment duration
Для цитирования

Байызбекова Э.А.Тревога и депрессия у пациентов с туберкулезом в Кыргызстане: распространенность и взаимосвязь с возрастом и длительностью лечения. Научно-практический журнал «Здравоохранение Кыргызстана» 2026, № 1, с. 102-109.  https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
For citation

Baiyzbekova E.A. Anxiety and depression among tuberculo sis patients in Kyrgyzstan:prevalence and associations with age and treatment duration. Scientific and practical journal “Health care of Kyrgyzstan 2026, No.1, p. 102-109.  https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
Цитата үчүн

Байызбекова Э.А. Кыргызстандагы кургак учук менен ооругандардагы тынчсыздануу жана депрессия: таралышы жана жаш курак менен дарылоо узактыгы боюнча байланышы. Кыргызстандын саламаттык сактоо илимий-практикалык журналы 2026, № 1 б. 102-109. https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
Authors Baiyzbekova E.A.
Link doi.org https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
Pages 102-109
Keywords Age, Kyrgyzstan, Tuberculosis, Anxiety, Depression, HADS, Mental health, Treatment duration
Russian
Об авторах

Байызбекова Эльмира Алчинбековна, специалист по укреплению здоровья Центра медицины окружающей среды, экологии человека и питания, Национального института общественного здоровья Министерства здравоохранения, Бишкек, Кыргызская Республика

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Список литературы

1. Agbeko C.K., Mallah M.A., He B., Liu Q., Song H., Wang J. Mental Health Status and Its Impact on TB Treatment and Its Out comes: A Scoping Literature Review. Frontiers in Public Health. 2022;10:855515. DOI: 10.3389/fpubh.2022.855515. URL: https://www.frontiersin.org/articles/10.3389/fpubh.2022.855515/full

2. Ambaw F., Mayston R., Hanlon C., Alem A. Incidence of depression in people with newly diagnosed tuberculosis in Ethiopia: a cohort study. Global Mental Health. 2020;7:e1. DOI: https://doi.org/10.1017/gmh.2019.27 URL: https://www.cambridge.org/core/journals/global-mental-health/article/incidence-of-depression-in-people-with-newly-diag nosed-tuberculosis-in-ethiopia-a-cohort-study/D31BBF368691480D0FCEAD5FAC7A86DF?utm_source=chatgpt.com

3. Duko B., Bedaso A., Ayano G. The prevalence of depression among patients with tuberculosis: a systematic review and meta- analysis. Annals of General Psychiatry. 2020;19:30. DOI: 10.1186/s12991-020-00281-8. URL: https://annals-general-psychiatry. biomedcentral.com/articles/10.1186/s12991-020-00281-8

4. Fukunaga R, Pierre P, Williams JK, Briceno-Robaugh R, Kalibala S, Peterson M, et al. Prioritizing Mental Health within HIV and Tuberculosis Services in PEPFAR. Emerg Infect Dis. 2024;30(4):1-5. DOI: 10.3201/eid3004.231726 URL: https://wwwnc.cdc. gov/eid/article/30/4/23-1726_article

5. Lee G., Scuffell J., Galea J.T., Shin S.S., Magill E., Jaramillo E., Sweetland A.C. Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis. International Journal of Tuberculosis and Lung Disease. 2020;24(12):1279– 1284. DOI: 10.5588/ijtld.20.0458. URL: https://pubmed.ncbi.nlm.nih.gov/33317672/

6. Liu X., Bai X., Ren R., Tan L., Zhang Y., Lan H., Yang Q., He J., Tang X. Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study. Frontiers in Psychiatry. 2022;13:985823. DOI: 10.3389/fpsyt.2022.985823. URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.985823/full

7. Panibatla, V., Nagaraja, S. B., Mohan, D., Kizhakkethil, S. M. P., Sangeetha, M. D. Depression and Anxiety among Tuberculosis Patients: A Systematic Review and Meta-analysis. Indian Journal of Social Psychiatry 40(4):p 326-340, Oct–Dec 2024. DOI:10.4103/ijsp.ijsp_222_23. URL:https://journals.lww.com/ijsp/fulltext/2024/40040/ depression_and_anxiety_ among_tuber culosis. 2.aspx

8. Patel, N., Patel, H., Varu, J., Gandhi, R., Murugan, Y. The Invisible Toll: Unveiling the Prevalence and Predictors of Depression and Anxiety Among Pulmonary Tuberculosis (TB) Patients and Their Households in Gujarat, India. Cureus. 2024;16(7):e65015. DOI: 10.7759/cureus.65015. URL: https://www.cureus.com/articles/275659-the-invisible-toll-unveiling-the-prevalence-and-pre dictors-of-depression-and-anxiety-among-pulmonary-tuberculosis-tb-patients-and-their-households-in-gujarat-india

9. Samal J., Dehury R.K., Thomas M.B., Singh H. Prevalence and predictors of depression in tuberculosis patients in India: a syste- matic review and meta-analysis. Discover Mental Health. 2025;5(1):104. DOI: 10.1007/s44192-025-00248-9. URL: https://pub- med.ncbi.nlm.nih.gov/40650839/

10. Shen R., Zong K., Liu J., Zhang L. Risk Factors for Depression in Tuberculosis Patients: A Meta-Analysis. Neuropsychiatric Disease and Treatment. 2022;18:847–866. DOI: 10.2147/NDT.S347579. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC 9012238/

11. World Health organization. Global tuberculosis report 2022. Geneva; 2022. URL: https://iris.who.int/bitstream/handle/10665/363 752/ 9789240061729-eng.pdf

12. World Health Organization. World mental health report: transforming mental health for all. Geneva; 2022. URL:https://iris.who.int/ bitstream /handle/10665/356119/9789240049338-eng.pdf

13. World Health Organization. WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities - mental health conditions. Geneva; 2023. URL: https://iris.who.int/bitstream/handle/10665/373829/9789240082557-eng.pdf

14. World Health Organization. Operational Handbook on Tuberculosis. Module 6: Tuberculosis and Comorbidities. Mental health conditions and substance use disorders. Section 3: Identifying and managing care for mental health conditions and substance use disorders in people affected by TB. WHO TB Knowledge Sharing Platform. URL: https://tbksp.who.int/en/node/2649
Для цитирования

Байызбекова Э.А.Тревога и депрессия у пациентов с туберкулезом в Кыргызстане: распространенность и взаимосвязь с возрастом и длительностью лечения. Научно-практический журнал «Здравоохранение Кыргызстана» 2026, № 1, с. 102-109.  https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
English
About authors

Baiyzbekova Elmira Alchinbekovna, Health Promotion Specialist, Center for Environmental Medicine, Human Ecology, and Nutrition, National Institute of Public Health, Ministry of Health, Bishkek, Kyrgyz Republic
Full text

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References

1. Agbeko C.K., Mallah M.A., He B., Liu Q., Song H., Wang J. Mental Health Status and Its Impact on TB Treatment and Its Out comes: A Scoping Literature Review. Frontiers in Public Health. 2022;10:855515. DOI: 10.3389/fpubh.2022.855515. URL: https://www.frontiersin.org/articles/10.3389/fpubh.2022.855515/full

2. Ambaw F., Mayston R., Hanlon C., Alem A. Incidence of depression in people with newly diagnosed tuberculosis in Ethiopia: a cohort study. Global Mental Health. 2020;7:e1. DOI: https://doi.org/10.1017/gmh.2019.27 URL: https://www.cambridge.org/core/journals/global-mental-health/article/incidence-of-depression-in-people-with-newly-diag nosed-tuberculosis-in-ethiopia-a-cohort-study/D31BBF368691480D0FCEAD5FAC7A86DF?utm_source=chatgpt.com

3. Duko B., Bedaso A., Ayano G. The prevalence of depression among patients with tuberculosis: a systematic review and meta- analysis. Annals of General Psychiatry. 2020;19:30. DOI: 10.1186/s12991-020-00281-8. URL: https://annals-general-psychiatry. biomedcentral.com/articles/10.1186/s12991-020-00281-8

4. Fukunaga R, Pierre P, Williams JK, Briceno-Robaugh R, Kalibala S, Peterson M, et al. Prioritizing Mental Health within HIV and Tuberculosis Services in PEPFAR. Emerg Infect Dis. 2024;30(4):1-5. DOI: 10.3201/eid3004.231726 URL: https://wwwnc.cdc. gov/eid/article/30/4/23-1726_article

5. Lee G., Scuffell J., Galea J.T., Shin S.S., Magill E., Jaramillo E., Sweetland A.C. Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis. International Journal of Tuberculosis and Lung Disease. 2020;24(12):1279– 1284. DOI: 10.5588/ijtld.20.0458. URL: https://pubmed.ncbi.nlm.nih.gov/33317672/

6. Liu X., Bai X., Ren R., Tan L., Zhang Y., Lan H., Yang Q., He J., Tang X. Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study. Frontiers in Psychiatry. 2022;13:985823. DOI: 10.3389/fpsyt.2022.985823. URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.985823/full

7. Panibatla, V., Nagaraja, S. B., Mohan, D., Kizhakkethil, S. M. P., Sangeetha, M. D. Depression and Anxiety among Tuberculosis Patients: A Systematic Review and Meta-analysis. Indian Journal of Social Psychiatry 40(4):p 326-340, Oct–Dec 2024. DOI:10.4103/ijsp.ijsp_222_23. URL:https://journals.lww.com/ijsp/fulltext/2024/40040/ depression_and_anxiety_ among_tuber culosis. 2.aspx

8. Patel, N., Patel, H., Varu, J., Gandhi, R., Murugan, Y. The Invisible Toll: Unveiling the Prevalence and Predictors of Depression and Anxiety Among Pulmonary Tuberculosis (TB) Patients and Their Households in Gujarat, India. Cureus. 2024;16(7):e65015. DOI: 10.7759/cureus.65015. URL: https://www.cureus.com/articles/275659-the-invisible-toll-unveiling-the-prevalence-and-pre dictors-of-depression-and-anxiety-among-pulmonary-tuberculosis-tb-patients-and-their-households-in-gujarat-india

9. Samal J., Dehury R.K., Thomas M.B., Singh H. Prevalence and predictors of depression in tuberculosis patients in India: a syste- matic review and meta-analysis. Discover Mental Health. 2025;5(1):104. DOI: 10.1007/s44192-025-00248-9. URL: https://pub- med.ncbi.nlm.nih.gov/40650839/

10. Shen R., Zong K., Liu J., Zhang L. Risk Factors for Depression in Tuberculosis Patients: A Meta-Analysis. Neuropsychiatric Disease and Treatment. 2022;18:847–866. DOI: 10.2147/NDT.S347579. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC 9012238/

11. World Health organization. Global tuberculosis report 2022. Geneva; 2022. URL: https://iris.who.int/bitstream/handle/10665/363 752/ 9789240061729-eng.pdf

12. World Health Organization. World mental health report: transforming mental health for all. Geneva; 2022. URL:https://iris.who.int/ bitstream /handle/10665/356119/9789240049338-eng.pdf

13. World Health Organization. WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities - mental health conditions. Geneva; 2023. URL: https://iris.who.int/bitstream/handle/10665/373829/9789240082557-eng.pdf

14. World Health Organization. Operational Handbook on Tuberculosis. Module 6: Tuberculosis and Comorbidities. Mental health conditions and substance use disorders. Section 3: Identifying and managing care for mental health conditions and substance use disorders in people affected by TB. WHO TB Knowledge Sharing Platform. URL: https://tbksp.who.int/en/node/2649
For citation

Baiyzbekova E.A. Anxiety and depression among tuberculo sis patients in Kyrgyzstan:prevalence and associations with age and treatment duration. Scientific and practical journal “Health care of Kyrgyzstan 2026, No.1, p. 102-109.  https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
Kyrgyz
Авторлор жөнүндө

Байызбекова Элмира Алчынбековна, Саламаттыкты сактоо министрлигинин Коомдук саламаттыкты сактоо боюнча улуттук институтунун Айлана-чөйрөнү коргоо медицинасы, адам экологиясы жана тамактануу борборунун Ден соолуктун чыңдоо боюнча адиси, Бишкек, Кыргыз Республикасы
Шилтемелер

1. Agbeko C.K., Mallah M.A., He B., Liu Q., Song H., Wang J. Mental Health Status and Its Impact on TB Treatment and Its Out comes: A Scoping Literature Review. Frontiers in Public Health. 2022;10:855515. DOI: 10.3389/fpubh.2022.855515. URL: https://www.frontiersin.org/articles/10.3389/fpubh.2022.855515/full

2. Ambaw F., Mayston R., Hanlon C., Alem A. Incidence of depression in people with newly diagnosed tuberculosis in Ethiopia: a cohort study. Global Mental Health. 2020;7:e1. DOI: https://doi.org/10.1017/gmh.2019.27 URL: https://www.cambridge.org/core/journals/global-mental-health/article/incidence-of-depression-in-people-with-newly-diag nosed-tuberculosis-in-ethiopia-a-cohort-study/D31BBF368691480D0FCEAD5FAC7A86DF?utm_source=chatgpt.com

3. Duko B., Bedaso A., Ayano G. The prevalence of depression among patients with tuberculosis: a systematic review and meta- analysis. Annals of General Psychiatry. 2020;19:30. DOI: 10.1186/s12991-020-00281-8. URL: https://annals-general-psychiatry. biomedcentral.com/articles/10.1186/s12991-020-00281-8

4. Fukunaga R, Pierre P, Williams JK, Briceno-Robaugh R, Kalibala S, Peterson M, et al. Prioritizing Mental Health within HIV and Tuberculosis Services in PEPFAR. Emerg Infect Dis. 2024;30(4):1-5. DOI: 10.3201/eid3004.231726 URL: https://wwwnc.cdc. gov/eid/article/30/4/23-1726_article

5. Lee G., Scuffell J., Galea J.T., Shin S.S., Magill E., Jaramillo E., Sweetland A.C. Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis. International Journal of Tuberculosis and Lung Disease. 2020;24(12):1279– 1284. DOI: 10.5588/ijtld.20.0458. URL: https://pubmed.ncbi.nlm.nih.gov/33317672/

6. Liu X., Bai X., Ren R., Tan L., Zhang Y., Lan H., Yang Q., He J., Tang X. Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study. Frontiers in Psychiatry. 2022;13:985823. DOI: 10.3389/fpsyt.2022.985823. URL: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.985823/full

7. Panibatla, V., Nagaraja, S. B., Mohan, D., Kizhakkethil, S. M. P., Sangeetha, M. D. Depression and Anxiety among Tuberculosis Patients: A Systematic Review and Meta-analysis. Indian Journal of Social Psychiatry 40(4):p 326-340, Oct–Dec 2024. DOI:10.4103/ijsp.ijsp_222_23. URL:https://journals.lww.com/ijsp/fulltext/2024/40040/ depression_and_anxiety_ among_tuber culosis. 2.aspx

8. Patel, N., Patel, H., Varu, J., Gandhi, R., Murugan, Y. The Invisible Toll: Unveiling the Prevalence and Predictors of Depression and Anxiety Among Pulmonary Tuberculosis (TB) Patients and Their Households in Gujarat, India. Cureus. 2024;16(7):e65015. DOI: 10.7759/cureus.65015. URL: https://www.cureus.com/articles/275659-the-invisible-toll-unveiling-the-prevalence-and-pre dictors-of-depression-and-anxiety-among-pulmonary-tuberculosis-tb-patients-and-their-households-in-gujarat-india

9. Samal J., Dehury R.K., Thomas M.B., Singh H. Prevalence and predictors of depression in tuberculosis patients in India: a syste- matic review and meta-analysis. Discover Mental Health. 2025;5(1):104. DOI: 10.1007/s44192-025-00248-9. URL: https://pub- med.ncbi.nlm.nih.gov/40650839/

10. Shen R., Zong K., Liu J., Zhang L. Risk Factors for Depression in Tuberculosis Patients: A Meta-Analysis. Neuropsychiatric Disease and Treatment. 2022;18:847–866. DOI: 10.2147/NDT.S347579. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC 9012238/

11. World Health organization. Global tuberculosis report 2022. Geneva; 2022. URL: https://iris.who.int/bitstream/handle/10665/363 752/ 9789240061729-eng.pdf

12. World Health Organization. World mental health report: transforming mental health for all. Geneva; 2022. URL:https://iris.who.int/ bitstream /handle/10665/356119/9789240049338-eng.pdf

13. World Health Organization. WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities - mental health conditions. Geneva; 2023. URL: https://iris.who.int/bitstream/handle/10665/373829/9789240082557-eng.pdf

14. World Health Organization. Operational Handbook on Tuberculosis. Module 6: Tuberculosis and Comorbidities. Mental health conditions and substance use disorders. Section 3: Identifying and managing care for mental health conditions and substance use disorders in people affected by TB. WHO TB Knowledge Sharing Platform. URL: https://tbksp.who.int/en/node/2649
Цитата үчүн

Байызбекова Э.А. Кыргызстандагы кургак учук менен ооругандардагы тынчсыздануу жана депрессия: таралышы жана жаш курак менен дарылоо узактыгы боюнча байланышы. Кыргызстандын саламаттык сактоо илимий-практикалык журналы 2026, № 1 б. 102-109. https://dx.doi.org/10.51350/zdravkg2026.1.3.12.102.109
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